Latest news from ACIU

AC Immune Positive Interim Phase 2 Data on ACI-7104.056 Support Potential Slowing of Progression of Parkinson’s Disease

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News from ACIU

AC Immune And Takeda Sign Exclusive Option And License Agreement For Active Immunotherapy Targeting Amyloid Beta For Alzheimer’s Disease

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Targeting misfolded self-proteins

Pioneering precision medicine for neurodegeneration

Monitoring patients’ specific proteinopathies, enables well-timed selection of the most appropriate therapeutic(s).

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Prevention through early and safe intervention

Developing active immunotherapy strategies to prevent Alzheimer's and Parkinson's disease

Neurodegeneration is a slow, silent pandemic. It is a moral and economic imperative to address it. Preserving neurons and preventing disease is the most promising strategy.

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AC Immune’s technology platforms

Morphomer® and Supraantigen® platforms deliver best-in-class small molecules and biologics

Discover the technologies that generated our differentiated pipeline of diagnostic and therapeutic candidates

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AC Immune is pioneering new ways to diagnose, treat and prevent neurodegeneration

AC Immune SA, a clinical-stage biopharmaceutical company, is a global leader in developing precision medicine for neurodegenerative diseases, including Alzheimer’s disease, Parkinson’s disease, and certain rare indications. We are addressing the social and economic imperative created by the growing incidence of neurodegenerative diseases.

Our deep knowledge and cutting-edge technology platforms are the engines for our diverse pipeline of clinical and preclinical product candidates including active immunotherapies, antibodies, small molecule drugs and diagnostic agents. We have pioneered scientific and clinical advances in the understanding and treatment of neurodegeneration.

Our scientific leadership, technologies and pipeline have been validated by our collaboration partnerships with global pharmaceutical leaders: Janssen Pharmaceuticals, Takeda and Eli Lilly and Co.

Dr Andrea Pfeifer, a co-founder of AC Immune in 2003 and the founding CEO, announced the retirement from her role as CEO in May 2026. Following the Annual General Meeting of shareholders in June 2026, she was appointed to the role of Honorary Chair of the Board of Directors and Advisor to the company.

Dr Pfeifer shaped the company into a resilient, innovation-driven, pioneering clinical-stage biopharmaceutical company developing precision therapeutics for neurodegenerative diseases. Under her leadership the company completed its Nasdaq IPO in 2016. She led with clarity of vision and integrity, consistently championing the company’s long-term potential. We are deeply grateful to Dr Pfeifer for the exceptional contribution she made to AC Immune and are delighted that she remains closely connected with the company.

AC Immune is shaping the future of neurodegeneration by discovering and developing breakthrough therapies through pioneering science and precision medicine.

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Facts & Figures

>50 Million

People worldwide living
with Dementia

>$1 Trillion

Global annual
Cost of Dementia

>6 Million

People worldwide living
with Parkinson's

>8 Million

People living with different
NeuroOrphan diseases in the U.S.

Addressing Alzheimer’s, Parkinson’s and other neurodegenerative diseases

BROAD AND DIVERSIFIED PIPELINE FOCUSED ON NEURODEGENERATIVE DISEASES

Our clinical stage pipeline uniquely integrates diagnostic and therapeutic candidates as well as different treatment modalities (such as antibodies, active immunotherapies and small molecule drugs) against the most promising validated therapeutic targets.

Pioneering Precision Medicine

AC Immune develops the tools to enable detection and clearance of pathological proteins underlying neurodegenerative diseases. Identifying and targeting these misfolded proteins and related pathways in each patient will be key to achieving best possible efficacy.

AC Immune | Pioneering Precision Medicine for neurodegenerative diseases