In May 2014, AC Immune signed its first diagnostic partnership, with Life Molecular Imaging SA (formerly Piramal Imaging SA). This exclusive worldwide out-licensing agreement for a Tau protein Positron Emission Tomography (PET) tracer PI-2620 supporting the early diagnosis and clinical management of Alzheimer’s disease and other Tau-related disorders, such as progressive supranuclear palsy (PSP). The agreement includes upfront and sales milestone payments totaling up to EUR 160 million, plus royalties.